Linked Life Data

6885603

Source:http://linkedlifedata.com/resource/pubmed/id/6885603

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-10-21
pubmed:abstractText
The effect of xylazine on the transit of barium sulfate through the stomach and duodenum was evaluated in 4 dogs. Base-line transit time was determined while the dogs were nonsedated and undisturbed; the mean time for barium sulfate to move from the stomach to the duodenojejunal junction was 4.8 +/- 1.2 minutes. An IV injection of xylazine (1 mg/kg) prolonged the mean transit time to 157 +/- 37.8 minutes. During the xylazine-induced prolongation of gastrointestinal transit, there were no vigorous contractions for at least 90 minutes. Yohimbine, an alpha 2-adrenergic-blocking agent, given IV at a dosage of 0.1 mg/kg, did not affect gastrointestinal motility. It did, however, prevent both the gastrointestinal and sedative effects of xylazine. Atropine methylnitrate given IV at a dosage of 1 mg/kg prolonged the transit time to 13.8 +/- 2.4 minutes. After atropine methylnitrate injection, the gastrointestinal tract was more flaccid than with xylazine administration. The prolongation of transit induced by atropine methylnitrate was not prevented by yohimbine. It was concluded that gastrointestinal radiographic findings in animals under the influence of xylazine should be interpreted cautiously.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0003-1488
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
183
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
297-300
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Effect of yohimbine on xylazine-induced prolongation of gastrointestinal transit in dogs.
pubmed:publicationType
Journal Article, Comparative Study