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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1983-10-28
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pubmed:abstractText |
The respiratory burst of polymorphonuclear leukocytes, induced by the addition of chemotactic peptide (N-formyl-methionyl-leucyl-phenylalanine) and cytochalasin B was found to consist of two phases. The first phase of very rapid oxygen uptake lasted 1-3 min. and was followed by a second more prolonged phase of lower magnitude. The apparent Km for oxygen of unstimulated cells was 9.6 +/- 0.67 microM, while that of the second phase of stimulation was 3.7 +/- 1.6 microM oxygen. The possibility that lowered oxygen concentrations may regulate polymorphonuclear leukocyte activity in some pathological conditions is discussed.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0014-5793
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
5
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pubmed:volume |
161
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
60-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6884528-Animals,
pubmed-meshheading:6884528-Chemotaxis, Leukocyte,
pubmed-meshheading:6884528-Cytochalasin B,
pubmed-meshheading:6884528-Kinetics,
pubmed-meshheading:6884528-N-Formylmethionine,
pubmed-meshheading:6884528-N-Formylmethionine Leucyl-Phenylalanine,
pubmed-meshheading:6884528-Neutrophils,
pubmed-meshheading:6884528-Oligopeptides,
pubmed-meshheading:6884528-Oxygen,
pubmed-meshheading:6884528-Oxygen Consumption,
pubmed-meshheading:6884528-Rats
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pubmed:year |
1983
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pubmed:articleTitle |
Decrease in apparent Km for oxygen after stimulation of respiration of rat polymorphonuclear leukocytes.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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