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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1983-10-28
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pubmed:abstractText |
10 patients with ischemic cerebral lesions were treated with 1,200-1,500 mg parenteral pentoxifylline daily for 10 days. The following rheological parameters were determined before treatment and every third day after the start of treatment: erythrocyte deformability and aggregation, hematocrit, plasma viscosity and yield shear stress. 2 patients were submitted to isovolemic hemodilution. Among all rheological parameters, the erythrocyte deformability and the yield shear stress improved significantly, whereas plasma viscosity and erythrocyte aggregation did not change. 1 patient died 20 days after admission. 9 patients improved clinically. Because of the small number of patients correlations between clinical outcome and therapy are not possible.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0014-3022
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
22 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
98-104
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6884407-Adult,
pubmed-meshheading:6884407-Aged,
pubmed-meshheading:6884407-Blood Viscosity,
pubmed-meshheading:6884407-Brain Ischemia,
pubmed-meshheading:6884407-Erythrocyte Aggregation,
pubmed-meshheading:6884407-Erythrocytes,
pubmed-meshheading:6884407-Female,
pubmed-meshheading:6884407-Hematocrit,
pubmed-meshheading:6884407-Hemodilution,
pubmed-meshheading:6884407-Humans,
pubmed-meshheading:6884407-Male,
pubmed-meshheading:6884407-Middle Aged,
pubmed-meshheading:6884407-Pentoxifylline,
pubmed-meshheading:6884407-Plasma,
pubmed-meshheading:6884407-Rheology,
pubmed-meshheading:6884407-Theobromine
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pubmed:year |
1983
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pubmed:articleTitle |
The rheological efficiency of parenteral pentoxifylline (Trental) in patients with ischemic brain lesions. Preliminary results.
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pubmed:publicationType |
Journal Article
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