Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1983-10-21
|
pubmed:abstractText |
Using our electron microscopic method of polysome analysis we ascertained the numbers of membrane-bound polysomes and their constituent ribosomes in myeloma cells of J 606 (IgG3) and MOPC315 (IgA) parent cell lines and in their variants that did not produce and, accordingly, secrete either H- or L-chains. Both variants had far fewer membrane-bound polysomes than the respective parent lines. The polysome distribution curve drawn for each of these variants showed one peak at 5-6 ribosomes. In contrast to this finding, the distribution curves for the J 606 and MOPC315 parent lines gave two peaks. These observations on mouse myelomas strongly resembled those on human myelomas.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0006-5242
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
47
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
147-52
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:6882930-Animals,
pubmed-meshheading:6882930-Cytoplasm,
pubmed-meshheading:6882930-Genetic Variation,
pubmed-meshheading:6882930-Immunoglobulins,
pubmed-meshheading:6882930-Mice,
pubmed-meshheading:6882930-Multiple Myeloma,
pubmed-meshheading:6882930-Plasma Cells,
pubmed-meshheading:6882930-Polyribosomes
|
pubmed:year |
1983
|
pubmed:articleTitle |
Ultrastructural analysis of membrane-bound polysomes in mouse "nonsecretory" myeloma (nonproducing type).
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|