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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1978-11-18
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pubmed:abstractText |
Three continuous lines of mammary tumor cells (ZR-75-1, ZR-75-27, and ZR-75-30) have been established from malignant effusions of two women with breast cancer. Differentiated properties expressed by each cell line include: (a) epithelial morphology (by light and electron microscopy) resembling that of the parental tumors; (b) presence of receptors for estrogen and other steroid hormones; and (c) growth responsiveness to estrogen and/or progesterone. All three cell lines possess human karyotypes that differ from one another in modal chromosome number as well as in characteristic marker chromosomes. Two of the cultures (ZR-75-27 and ZR-75-30), although derived from the same patient, have stable differences in their karyotypes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0008-5472
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3352-64
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:688225-Breast Neoplasms,
pubmed-meshheading:688225-Caseins,
pubmed-meshheading:688225-Cell Division,
pubmed-meshheading:688225-Cell Line,
pubmed-meshheading:688225-Chromosome Aberrations,
pubmed-meshheading:688225-Female,
pubmed-meshheading:688225-Humans,
pubmed-meshheading:688225-Kinetics,
pubmed-meshheading:688225-Lactalbumin,
pubmed-meshheading:688225-Microscopy, Electron,
pubmed-meshheading:688225-Neoplasms, Experimental,
pubmed-meshheading:688225-Neoplasms, Hormone-Dependent,
pubmed-meshheading:688225-Receptors, Steroid,
pubmed-meshheading:688225-Thymidine
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pubmed:year |
1978
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pubmed:articleTitle |
Establishment and characterization of three new continuous cell lines derived from human breast carcinomas.
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pubmed:publicationType |
Journal Article
|