Linked Life Data

688068

Source:http://linkedlifedata.com/resource/pubmed/id/688068

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1978-12-2
pubmed:abstractText
Synaptic junctional complexes (SJCs), isolated by a procedure which preserves presynaptic dense projections (PDPs) contain as their major component a polypeptide (P55) which comigrates with tubulin on sodium dodecyl sulfate - polyacrylamide gels and another major polypeptide (P45) which comigrates with muscle actin. We report here the characterization of P55 and P45 by two-dimensional polyacrylamide gel electrophoresis and by peptide mapping of the radioiodinated polypeptides. Our results indicate that P55 and P45 are homologous with tubulin and actin respectively, in terms of molecular weight, protein charge, and primary structure. Comparison of the sodium dodecyl sulfate - polyacrylamide gel electrophoresis patterns of SJCs and postsynaptic densities (PSDs) indicates that P55 and P45 are associated mainly with PDPs but are also found in the PSD.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0008-4018
pubmed:author
pubmed:issnType
Print
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
820-30
pubmed:dateRevised
2000-12-18
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Actin-like and tubulin-like proteins in synaptic junctional complexes.
pubmed:publicationType
Journal Article