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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1983-9-23
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pubmed:abstractText |
Endothelial damage and repair in autogenous saphenous vein grafts was evaluated serially from 30 s to 9 months after implantation into the femoral arteries of 25 dogs. Light and scanning electron microscopy, quantitative morphometry and cytochemistry with specific rabbit antidog factor VIII-related antigen were used. These studies demonstrate: (1) early complete endothelial cell desquamation both on the venous graft and adjacent artery apparently related to dissection and suture; (2) differing early platelet activation on the venous and adjacent arterial wall, platelet aggregates were noted on the adjacent artery, whereas only adhesive platelets are noted on the exposed vein graft; (3) endothelial reconstitution being initiated after 10-15 days but not reaching completion even 9 months after implantation; (4) a mediointimal proliferation which is a constant feature. A unique cell possessing both fibroblastic and myocytic characteristics takes part in the process.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0014-312X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
230-40
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6873122-Animals,
pubmed-meshheading:6873122-Blood,
pubmed-meshheading:6873122-Cell Differentiation,
pubmed-meshheading:6873122-Dogs,
pubmed-meshheading:6873122-Endothelium,
pubmed-meshheading:6873122-Evaluation Studies as Topic,
pubmed-meshheading:6873122-Femoral Artery,
pubmed-meshheading:6873122-Histocytochemistry,
pubmed-meshheading:6873122-Microscopy, Electron, Scanning,
pubmed-meshheading:6873122-Platelet Adhesiveness,
pubmed-meshheading:6873122-Platelet Aggregation,
pubmed-meshheading:6873122-Saphenous Vein,
pubmed-meshheading:6873122-Time Factors,
pubmed-meshheading:6873122-Veins
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pubmed:year |
1983
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pubmed:articleTitle |
Immediate and long-term evolution of the blood-venous graft interface. Experimental study in dogs.
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pubmed:publicationType |
Journal Article
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