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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1983-9-23
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pubmed:abstractText |
Cerebral blood flow (CBF) and cerebral O2 metabolism (CMRO2) changes were measured in these studies during treatment with three reputed cerebral vasodilators: bradykinin, adenosine triphosphate (ATP) and increased arterial PCO2. Intracerebrovascular bradykinin infusions increased CMRO2 and CBF to a similar degree. Intramaxillary ATP infusions increased CBF to an extent greater than that required for increases seen in CMRO2. Hypercapnia increased CBF without a significant change in CMRO2. Results suggest that increases in cerebral metabolism may mediate most, some and none of the cerebrovascular changes produced by bradykinin, ATP or hypercapnia, respectively.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0305-1870
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
115-24
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6872330-Adenosine Triphosphate,
pubmed-meshheading:6872330-Animals,
pubmed-meshheading:6872330-Blood Pressure,
pubmed-meshheading:6872330-Bradykinin,
pubmed-meshheading:6872330-Cerebrovascular Circulation,
pubmed-meshheading:6872330-Female,
pubmed-meshheading:6872330-Goats,
pubmed-meshheading:6872330-Hypercapnia,
pubmed-meshheading:6872330-Microspheres,
pubmed-meshheading:6872330-Oxygen Consumption
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pubmed:articleTitle |
Cerebrovascular and metabolic effects of bradykinin, ATP and hypercapnia in the goat.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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