rdf:type |
|
lifeskim:mentions |
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0026239,
umls-concept:C0086045,
umls-concept:C0205266,
umls-concept:C0439300,
umls-concept:C1533691,
umls-concept:C1881189,
umls-concept:C1882726,
umls-concept:C2258044,
umls-concept:C2346484
|
pubmed:issue |
3
|
pubmed:dateCreated |
1983-8-11
|
pubmed:abstractText |
Carnitine palmitoyltransferase I in rat liver mitochondria preincubated with malonyl-CoA was more sensitive to inhibition by malonyl-CoA than was the enzyme in mitochondria preincubated in the absence of malonyl-CoA. For carnitine palmitoyltransferase I in mitochondria from starved animals this increase also resulted in the enzyme becoming significantly more sensitive than that in mitochondria assayed immediately after their isolation. Concentrations of malonyl-CoA that induced half the maximal degree of sensitization observed were 1-3 microM.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0264-6021
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
210
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
953-6
|
pubmed:dateRevised |
2009-11-18
|
pubmed:meshHeading |
pubmed-meshheading:6870813-Acyl Coenzyme A,
pubmed-meshheading:6870813-Acyltransferases,
pubmed-meshheading:6870813-Animals,
pubmed-meshheading:6870813-Carnitine O-Palmitoyltransferase,
pubmed-meshheading:6870813-Female,
pubmed-meshheading:6870813-Malonyl Coenzyme A,
pubmed-meshheading:6870813-Mitochondria, Liver,
pubmed-meshheading:6870813-Pregnancy,
pubmed-meshheading:6870813-Rats,
pubmed-meshheading:6870813-Starvation
|
pubmed:year |
1983
|
pubmed:articleTitle |
Increased sensitivity of carnitine palmitoyltransferase I activity to malonyl-CoA inhibition after preincubation of intact rat liver mitochondria with micromolar concentrations of malonyl-CoA in vitro.
|
pubmed:publicationType |
Journal Article,
In Vitro
|