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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1983-8-11
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pubmed:abstractText |
The development of a mercury-195m/gold-195m radionuclide generator system is described, together with the results of preliminary experiments in animals and in man. The daughter radionuclide has a half-life of 30.5 s with a principal gamma emission at 262 keV, ideal for use with the multicrystal camera but suitable also in conjunction with the Anger design. The half-life of the parent radionuclide is 40 h. The eluant in current use is 2.5 mM sodium cyanide, the column being stored under 2% sodium nitrate solution when not in use to prevent radiation damage. Generators capable of delivering 550 MBq of 195Aum in a 0.4 ml bolus have been used for first-pass nuclear angiocardiography, the half-life being long enough to permit administration via peripheral intravenous injection. The radiation dose associated with this radionuclide is much lower than that from conventional 99Tcm-labelled radiopharmaceuticals, permitting multiple sequential studies, even on children.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0031-9155
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
139-47
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6867103-Animals,
pubmed-meshheading:6867103-Cyanides,
pubmed-meshheading:6867103-Dogs,
pubmed-meshheading:6867103-Erythrocytes,
pubmed-meshheading:6867103-Gold Radioisotopes,
pubmed-meshheading:6867103-Heart,
pubmed-meshheading:6867103-Humans,
pubmed-meshheading:6867103-Injections, Intravenous,
pubmed-meshheading:6867103-Mercury Radioisotopes,
pubmed-meshheading:6867103-Rabbits,
pubmed-meshheading:6867103-Radionuclide Generators,
pubmed-meshheading:6867103-Swine,
pubmed-meshheading:6867103-Thiocyanates
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pubmed:year |
1983
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pubmed:articleTitle |
A 195Hgm-195Aum generator for use in first-pass nuclear angiocardiography.
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pubmed:publicationType |
Journal Article
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