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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1983-7-29
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pubmed:abstractText |
Data on 164 patients treated at the Cleveland Clinic with gastric adenocarcinoma during the ten year period 1970 to 1980 was analyzed. Fiberoptic esophagogastroduodenoscopy was introduced as a routine diagnostic modality during this time and yielded a positive tissue diagnosis in 86% of patients in this series. Laparotomy was performed on 150 patients; 49 patients (30%) were biopsied only, 19 (12%) were bypassed for palliation, and 82 (58%) underwent gastrectomy. Of the latter group, only 45 patients (27%) were resected for cure. The overall operative mortality rate was 6%. All patients were staged according to the International TNM classification (stage I--10%, II--24%, III--12%, and IV--53%). Survival at 5 years was influenced by tumor location and extent of gastric resection but was most significantly related to stage of disease at operation (stage I--65%, II--22%, III--5%, and IV--0%; p less than 0.0001) and to the status of regional nodes (positive--17%, negative--56%; p less than 0.005). Despite the routine use of fiberoptic endoscopy, the majority of gastric cancers were advanced at diagnosis and their prognosis remains discouraging. Improvement of results will require a more aggressive approach to the endoscopic investigation of upper gastrointestinal symptoms and earlier surgical intervention.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6859997-13598782,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6859997-4124848,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6859997-5476798,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6859997-7093911,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6859997-7212802,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6859997-758866,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6859997-848677
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0003-4932
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
198
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
9-12
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6859997-Adenocarcinoma,
pubmed-meshheading:6859997-Duodenoscopy,
pubmed-meshheading:6859997-Esophagoscopy,
pubmed-meshheading:6859997-Gastroscopy,
pubmed-meshheading:6859997-Humans,
pubmed-meshheading:6859997-Laparotomy,
pubmed-meshheading:6859997-Lymphatic Metastasis,
pubmed-meshheading:6859997-Neoplasm Staging,
pubmed-meshheading:6859997-Prognosis,
pubmed-meshheading:6859997-Stomach Neoplasms,
pubmed-meshheading:6859997-Time Factors
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pubmed:year |
1983
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pubmed:articleTitle |
Gastric carcinoma. A ten-year review.
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pubmed:publicationType |
Journal Article,
Comparative Study
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