Linked Life Data

6855634

Source:http://linkedlifedata.com/resource/pubmed/id/6855634

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-7-8
pubmed:abstractText
The organization of plasmalemmal vesicular profiles in the endothelium of rat heart capillaries has been reinvestigated. Judged from random thin sections approximately 50% of the vesicles appeared free in the cytoplasm, the rest opening to the surfaces of the endothelial cells--a distribution which corroborates previous studies. However, three-dimensional reconstructions based on ultrathin serial sections (thickness congruent to 12 nm) gave a very different picture. All plasmalemmal vesicular profiles (921 from 5 capillaries) were parts of the surface membrane either as caveolae or as more complex racemose invaginations. This organization has previously been observed in frog mesenteric capillaries ((M. Bundgaard, J. Frøkjaer-Jensen, and C. Crone, 1979, Proc. Nat. Acad. Sci. USA 76, 6439-6442) and (J. Frøkjaer-Jensen, 1980, J. Ultrastruct. Res. 73, 9-20)). It is therefore proposed that absence or extreme rarity of free plasmalemmal vesicles is a general feature of capillary endothelia. Consequently, we suggest that the term "endothelial, plasmalemmal vesicles" be replaced by "endothelial plasmalemmal invaginations." The results imply that trans-endothelial vesicular transport is unlikely to occur and that this membrane system performs other--as yet unknown--functions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0026-2862
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
358-68
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
The three-dimensional organization of plasmalemmal vesicular profiles in the endothelium of rat heart capillaries.
pubmed:publicationType
Journal Article