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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1983-6-10
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pubmed:abstractText |
Natural host resistance to Pseudomonas aeruginosa corneal infection is regulated by two complementing dominant genes PsCR1 and PsCR2 (RS Berk, MA Leon, LD Hazlett. Infect Immun 26:1221-1223, 1979). In this study we have demonstrated a third dominant gene, which determines susceptibility to P. aeruginosa-induced eye damage. This gene was designated as PsCS. The F1 progeny from matings between the resistant DBA/2J strain and the susceptible strain C57BL/6J and C3H/HeJ displayed the susceptibility phenotype. Backcross and F2 studies using the C3H/HeJ and DBA/2J strains suggested the presence of two linked PsCS loci.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0037-9727
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
172
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
488-91
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:6844357-Animals,
pubmed-meshheading:6844357-Corneal Diseases,
pubmed-meshheading:6844357-Immunity, Innate,
pubmed-meshheading:6844357-Mice,
pubmed-meshheading:6844357-Mice, Inbred Strains,
pubmed-meshheading:6844357-Pseudomonas Infections,
pubmed-meshheading:6844357-Species Specificity
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pubmed:year |
1983
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pubmed:articleTitle |
Dominant susceptibility effect on the murine corneal response to Pseudomonas aeruginosa.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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