Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1983-6-17
|
pubmed:abstractText |
Serum transcobalamin (TC) levels were determined daily in 14 adults suffering from advanced nonhematological malignancies and hospitalized because of chemotherapy-induced leukopenia and fever. Even during the nadir leukocyte count, TCI and TCIII serum levels were normal or only slightly decreased indicating that bone marrow activity was not completely suppressed. A significant increase in serum TCII level was observed in all patients, with peak values occurring an average of 4.5 days from admission at a time when the median leukocyte count was 2,300/mm 3. Full white cell count recovery followed this peak TCII elevation within a mean of 5.5 days in all patients, coinciding with a fall in TCII levels to basal values. The rise in serum TCII level appears to be an early indicator for imminent bone marrow recovery in myelosuppressed patients.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0030-2414
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
40
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
218-22
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:6843947-Agranulocytosis,
pubmed-meshheading:6843947-Antineoplastic Agents,
pubmed-meshheading:6843947-Blood Proteins,
pubmed-meshheading:6843947-Clinical Laboratory Techniques,
pubmed-meshheading:6843947-Humans,
pubmed-meshheading:6843947-Leukocyte Count,
pubmed-meshheading:6843947-Neoplasms,
pubmed-meshheading:6843947-Transcobalamins
|
pubmed:year |
1983
|
pubmed:articleTitle |
Prognostic significance of changes in serum transcobalamin levels in cancer patients with chemotherapy-induced granulocytopenia.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|