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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1983-6-17
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pubmed:abstractText |
Thirty-three patients with acute nonlymphocytic leukemia were studied during remission-induction treatment in a double-blind, placebo-controlled, randomized study to ascertain the effect on the incidence of infection of an oral regimen of selective antimicrobial modulation (SAM). A decrease in the number of major acquired infections was observed: three infections occurred in 16 patients receiving the SAM regimen compared with eight infections in 17 patients given the placebo. The reduction of infection was correlated with a reduction of fever, with a reduction of the frequency of administration of antimicrobial agents for the treatment of infection, and with the selective elimination of aerobic and facultative anaerobic gram-negative rods from the digestive tract. Substantial unfavorable side effects were not observed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
147
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
615-23
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6842002-Adolescent,
pubmed-meshheading:6842002-Adult,
pubmed-meshheading:6842002-Aged,
pubmed-meshheading:6842002-Agranulocytosis,
pubmed-meshheading:6842002-Anti-Bacterial Agents,
pubmed-meshheading:6842002-Bacteria,
pubmed-meshheading:6842002-Bacterial Infections,
pubmed-meshheading:6842002-Double-Blind Method,
pubmed-meshheading:6842002-Female,
pubmed-meshheading:6842002-Fever,
pubmed-meshheading:6842002-Humans,
pubmed-meshheading:6842002-Intestines,
pubmed-meshheading:6842002-Leukemia,
pubmed-meshheading:6842002-Male,
pubmed-meshheading:6842002-Middle Aged,
pubmed-meshheading:6842002-Patient Compliance,
pubmed-meshheading:6842002-Random Allocation
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pubmed:year |
1983
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pubmed:articleTitle |
Selective antimicrobial modulation of the intestinal flora of patients with acute nonlymphocytic leukemia: a double-blind, placebo-controlled study.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|