Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-6-10
pubmed:abstractText
The role of the cytolytic toxin pneumolysin in the pathogenicity of Streptococcus pneumoniae was investigated. Pneumolysin was purified to homogeneity and used to immunize mice. When these mice were subsequently challenged via the nasal route with virulent S. pneumoniae, they survived significantly longer than control mice. The mean survival times were 5.52 and 2.48 days for immunized and control mice, respectively. This work provides direct evidence for the involvement of pneumolysin in pneumococcal pathogenicity.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6840851-13514230, http://linkedlifedata.com/resource/pubmed/commentcorrection/6840851-14907713, http://linkedlifedata.com/resource/pubmed/commentcorrection/6840851-240276, http://linkedlifedata.com/resource/pubmed/commentcorrection/6840851-2621, http://linkedlifedata.com/resource/pubmed/commentcorrection/6840851-4388678, http://linkedlifedata.com/resource/pubmed/commentcorrection/6840851-4398340, http://linkedlifedata.com/resource/pubmed/commentcorrection/6840851-4404325, http://linkedlifedata.com/resource/pubmed/commentcorrection/6840851-4404668, http://linkedlifedata.com/resource/pubmed/commentcorrection/6840851-5432063, http://linkedlifedata.com/resource/pubmed/commentcorrection/6840851-5806584, http://linkedlifedata.com/resource/pubmed/commentcorrection/6840851-6154745, http://linkedlifedata.com/resource/pubmed/commentcorrection/6840851-7298179, http://linkedlifedata.com/resource/pubmed/commentcorrection/6840851-7358434, http://linkedlifedata.com/resource/pubmed/commentcorrection/6840851-942051
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0019-9567
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
548-52
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Effect of immunization with pneumolysin on survival time of mice challenged with Streptococcus pneumoniae.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't