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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1983-6-10
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pubmed:abstractText |
The concentration of alpha 2HS-glycoprotein was measured in the serum and urine of normal individuals and of patients with osteogenesis imperfecta. The serum concentration of alpha 2HS-glycoprotein was higher in normal children than in adults. In women values showed a progressive age-related decrease, from 632 mg/l at 21-30 years to 573 mg/l at 51-60 years. In men there was no such age-related variation, and values were higher than in women of comparable age; the mean value for men aged 20-60 years was 648 mg/l. Of 48 patients with osteogenesis imperfecta, 11 had an abnormally high concentration of alpha 2HS-glycoprotein in serum; the cause of this is not clear. In urine of 24 normal individuals the mean value of the ratio albumin: alpha 2HS-glycoprotein was 20 +/- 3; in serum the corresponding ratio was 70. Urine excretion of alpha 2HS-glycoprotein was lowest in female children (132 +/- 29 micrograms/24 h) and highest in male adults (592 +/- 91 micrograms/24 h); values in patients with osteogenesis imperfecta did not differ from normal.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0171-967X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
16-20
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:6839187-Adolescent,
pubmed-meshheading:6839187-Adult,
pubmed-meshheading:6839187-Aging,
pubmed-meshheading:6839187-Blood Proteins,
pubmed-meshheading:6839187-Bone and Bones,
pubmed-meshheading:6839187-Child,
pubmed-meshheading:6839187-Female,
pubmed-meshheading:6839187-Humans,
pubmed-meshheading:6839187-Immunoelectrophoresis,
pubmed-meshheading:6839187-Male,
pubmed-meshheading:6839187-Osteogenesis Imperfecta,
pubmed-meshheading:6839187-Reference Values,
pubmed-meshheading:6839187-Sex Factors,
pubmed-meshheading:6839187-alpha-2-HS-Glycoprotein
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pubmed:year |
1983
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pubmed:articleTitle |
Variations in the serum concentration and urine excretion of alpha 2HS-glycoprotein, a bone-related protein, in normal individuals and in patients with osteogenesis imperfecta.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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