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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8025
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pubmed:dateCreated |
1977-7-29
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pubmed:abstractText |
A renal transplant involving a recipient with a positive serological cross-match against donor lymphocytes generally results in hyperacute rejection of the graft. 13 cadaveric renal transplants were performed in recipients with a known positive serologic cross-match against donor B lymphocytes. 12 of these serological cross-matches were positive against donor blood, node, or spleen lymphocytes, but the reactivity was directed against donor B lymphocytes only. 3 transplants failed, 2 because of rejection and 1 because of renal-artery thrombosis. 10 transplants are functioning, 6 to 42 weeks after the operation. Of these 10 successful grafts, 3 had no acute rejection episodes, while 7 had an early acute rejection episode which responded to treatment. Histologically, the grafts showed a cellular rejection, similar to that in enhanced renal allografts in the rat. It is possible to transplant a kidney in a high-risk patient with a positive B lymphocyte cross-match with a low risk of failure. In addition active enhancement of the graft might sometimes occur.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
18
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1288-91
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:68386-Acute Disease,
pubmed-meshheading:68386-B-Lymphocytes,
pubmed-meshheading:68386-Cadaver,
pubmed-meshheading:68386-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:68386-Female,
pubmed-meshheading:68386-Graft Rejection,
pubmed-meshheading:68386-Histocompatibility Testing,
pubmed-meshheading:68386-Humans,
pubmed-meshheading:68386-Kidney Transplantation,
pubmed-meshheading:68386-Male,
pubmed-meshheading:68386-Pregnancy,
pubmed-meshheading:68386-T-Lymphocytes,
pubmed-meshheading:68386-Transplantation, Homologous
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pubmed:year |
1977
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pubmed:articleTitle |
Renal transplantation and a positive serological cross-match.
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pubmed:publicationType |
Journal Article
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