Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1983-5-5
|
pubmed:abstractText |
For the study on the regulation of isoprenoid biosynthesis with intact cells, some strains of bacteria capable of growing on mevalonate as a sole carbon source were isolated from soil. Many of them incorporated [14C]-mevalonate, [14C]isopentenyl- and [14C]farnesyl pyrophosphates into the cells. However, radioactivity was found in their degradation products but not in isoprenoids. Addition of [14C]isopentenyl pyrophosphate, farnesyl pyrophosphate and Mg2+ ions in combination to the culture of a strain of Arthrobacter gave rise to 14C-incorporation into isoprenoids. Radioactivity was found in polyprenol, its pyrophosphate, monophosphate and fatty acid esters. The reactions of isopentenyl- and farnesyl pyrophosphates syntheses seemed to be rate-limiting steps.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0006-291X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
14
|
pubmed:volume |
110
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
187-93
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6838508-Bacteria,
pubmed-meshheading:6838508-Carbon Radioisotopes,
pubmed-meshheading:6838508-Kinetics,
pubmed-meshheading:6838508-Mevalonic Acid,
pubmed-meshheading:6838508-Polyisoprenyl Phosphates,
pubmed-meshheading:6838508-Structure-Activity Relationship,
pubmed-meshheading:6838508-Terpenes
|
pubmed:year |
1983
|
pubmed:articleTitle |
Studies on isoprenoid biosynthesis with bacterial intact cells.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|