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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1983-5-27
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pubmed:abstractText |
Scanning electron and transmission electron micrographs of tissue biopsies from experimental third-degree burns treated topically with 96% oxygen for twenty-five days, without modifying the environment of the whole animal, revealed a marked promotion of collagen maturation. The O2-treated wounds showed a high ratio of collagen-ground substance; assembling of distinct fibers to form bundles with individual fibers of 1,360 +/- 95 A in diameter and an organized orientation; a highly aggregated rough endoplasmic reticulum of the fibroblasts, consisting of large cisternae and abundant ribosomes. The control burn wounds exposed to ambient air exhibited a low ratio of collagen-ground substance; a loose, rough endoplasmic reticulum; fiber diameter of 700 +/- 70 A, with haphazard orientation of the fibers; and a poor tendency to form bundles. These findings suggest that topical treatment of experimental deep burns with 96% O2 promoted collagen maturation and organization as well as collagen synthesis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0148-7043
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
218-23
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6838132-Administration, Topical,
pubmed-meshheading:6838132-Animals,
pubmed-meshheading:6838132-Biopsy,
pubmed-meshheading:6838132-Burns,
pubmed-meshheading:6838132-Climate,
pubmed-meshheading:6838132-Collagen,
pubmed-meshheading:6838132-Connective Tissue,
pubmed-meshheading:6838132-Fibroblasts,
pubmed-meshheading:6838132-Guinea Pigs,
pubmed-meshheading:6838132-Humidity,
pubmed-meshheading:6838132-Microclimate,
pubmed-meshheading:6838132-Microscopy, Electron, Scanning,
pubmed-meshheading:6838132-Oxygen,
pubmed-meshheading:6838132-Skin
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pubmed:year |
1983
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pubmed:articleTitle |
The microclimate chamber: morphological aspects of experimental deep burns treated topically with continuous humidified oxygen.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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