Linked Life Data

6837259

Source:http://linkedlifedata.com/resource/pubmed/id/6837259

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-5-5
pubmed:abstractText
The development of birefringent lipids in pre- and postnatal rabbit lungs was studied by polarizing microscopy (PM) and correlated with transmission electron microscopy (TEM). Birefringent lipids first appeared as small scattered particles in the developing alveolar walls at 27 days of gestation. These particles became aggregated, gradually increased in amount in older fetuses, and reached a prenatal maximum at 30 days. Numerous particles were located in the alveolar lumen, beginning in the 30-day fetuses. Further increase in the amount of birefringent lipids occurred in the 60-day-old rabbits. TEM demonstrated cytoplasmic lipid inclusion bodies in the type II pneumocytes at 25 days of gestation. Some of these inclusions were lamellated, but regular lamellated bodies were often seen in older fetuses. It appears that the development of birefringent lipids is closely correlated with the development of lamellated bodies seen with TEM, and PM is a simple, useful method in following the development and maturation of surfactant lipids.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5180
pubmed:author
pubmed:issnType
Print
pubmed:volume
115
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
151-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Polarizing microscopy of birefringent lipids in rabbit fetal lungs.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.