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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4597
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pubmed:dateCreated |
1983-5-27
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pubmed:abstractText |
Plasma obtained from human subjects after exercise and injected intraperitoneally into rats elevated rat rectal temperature and depressed plasma iron and zinc concentrations. The pyrogenic component was heat-denaturable and had an apparent molecular weight of 14,000 daltons. Human mononuclear leukocytes obtained after exercise and incubated in vitro released a factor into the medium that also elevated body temperature in rats and reduced trace metal concentrations. These results suggest that endogenous pyrogen, a protein mediator of fever and trace metal metabolism during infection, is released during exercise.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0036-8075
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
6
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pubmed:volume |
220
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
617-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:6836306-Adult,
pubmed-meshheading:6836306-Animals,
pubmed-meshheading:6836306-Body Temperature,
pubmed-meshheading:6836306-Female,
pubmed-meshheading:6836306-Humans,
pubmed-meshheading:6836306-Interleukin-1,
pubmed-meshheading:6836306-Iron,
pubmed-meshheading:6836306-Leukocytes,
pubmed-meshheading:6836306-Male,
pubmed-meshheading:6836306-Molecular Weight,
pubmed-meshheading:6836306-Physical Exertion,
pubmed-meshheading:6836306-Proteins,
pubmed-meshheading:6836306-Pyrogens,
pubmed-meshheading:6836306-Rats,
pubmed-meshheading:6836306-Rats, Inbred Strains,
pubmed-meshheading:6836306-Zinc
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pubmed:year |
1983
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pubmed:articleTitle |
Endogenous pyrogen activity in human plasma after exercise.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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