Linked Life Data

6829179

Source:http://linkedlifedata.com/resource/pubmed/id/6829179

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-4-21
pubmed:abstractText
During filtration leukapheresis a factor(s) is produced, released or extracted into rat blood which causes a transient granulocytosis in pheresed animals and in recipients of homologous plasma from these animals. To identify which factors contribute to this granulocytosis, the procedural steps involved in filtration leukapheresis as well as a number of chemical agents which are potentially extracted from of produced by the procedure, were tested for their ability to stimulate granulocytosis. Procedural steps tested included the depth of anesthesia, effect of the anticoagulant and possible interactions of blood cells with the plastic tubing in the system (sham-pheresis). Chemical agents tested included common mediators of inflammation and proteinases released by polymorphonuclear leukocytes (PMNs), extracts of nylon fibers and Tygon tubing, nylon monomers and solvents used in the manufacture of nylon, oxidized and decomplemented plasma and lysates of PMNs or microorganisms. Our findings demonstrate that several of these agents contribute to the granulocytosis seen during filtration leukapheresis of rats.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0042-9007
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3-13
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Perturbations of granulocyte counts induced by procedural, chemical and physiological events occurring during filtration leukapheresis in rats.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.