Linked Life Data

6825764

Source:http://linkedlifedata.com/resource/pubmed/id/6825764

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-4-15
pubmed:abstractText
It has been observed that daily application of neostigmine onto the chorioallantoic membrane drastically reduced the total number of acetylcholine receptors in the superior oblique muscle of duck embryos. Here the effects of neostigmine on the magnitude of naturally occurring death of trochlear motor neurons during embryonic development were investigated. There was an enhanced loss of neurons in the neostigmine-treated embryos. Neostigmine neither affected the initial production of normal numbers of motor neurons nor had any direct toxic effect on their ultrastructure. The decrease in muscle activity did not always correlate with increased motor neuron survival. There may be a relationship between acetylcholine receptor distribution and naturally occurring neuronal death.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0014-4886
pubmed:author
pubmed:issnType
Print
pubmed:volume
79
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
801-7
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Decrease in acetylcholine receptor number correlated with increased naturally occurring trochlear motor neuron death during development.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.