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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1983-3-11
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pubmed:abstractText |
Glutathione peroxidase activity in platelets increased stepwise in selenium-depleted rats that were repleted with graded levels of dietary sodium selenite. In a 3-phase depletion/repletion/depletion feeding study, glutathione peroxidase activity was similar in platelets and liver, which apparently contains the largest labile pool of selenium in the body. The activity of glutathione S-transferase (selenium-independent glutathione peroxidase) in platelets was low and was not affected by selenium deficiency, even though hepatic transferase was markedly elevated in selenium-deficient rats. Vitamin E deficiency did not affect activities of glutathione peroxidase or glutathione S-transferase in platelets or liver. Determination of glutathione peroxidase activity in platelets apparently is a promising technique for assessing selenium status and, possibly, for measuring selenium bioavailability.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-3166
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
113
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
55-63
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6822891-Animals,
pubmed-meshheading:6822891-Biological Availability,
pubmed-meshheading:6822891-Blood Platelets,
pubmed-meshheading:6822891-Diet,
pubmed-meshheading:6822891-Glutathione Peroxidase,
pubmed-meshheading:6822891-Glutathione Transferase,
pubmed-meshheading:6822891-Liver,
pubmed-meshheading:6822891-Male,
pubmed-meshheading:6822891-Peroxidases,
pubmed-meshheading:6822891-Rats,
pubmed-meshheading:6822891-Rats, Inbred F344,
pubmed-meshheading:6822891-Selenium
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pubmed:year |
1983
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pubmed:articleTitle |
Platelet glutathione peroxidase activity as an index of selenium status in rats.
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pubmed:publicationType |
Journal Article
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