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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1983-3-11
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pubmed:abstractText |
One-hundred fifteen strain of Yersinia enterocolitica were examined for plasmids and plasmid-mediated pathogenic properties. Human strains of serotypes O:3 and O:9 harbored plasmids of 46 and 44 megadaltons, respectively, with 90% homology of DNA sequences. The plasmid-mediated properties were calcium dependence, survival in human serum, conjunctivitis provocation in guinea pigs, and O agglutinogens. One strains of serotype O:8 harbored a 42-megadalton plasmid with 75% sequence homology with plasmids of serotypes O:3 and O:9. An additional plasmid-mediated property was lethality for white mice. Filter hybridization of restriction endonuclease-digested plasmid DNA indicated that a 5.6-megadalton fragment of the plasmid of serotype O:8 had virtually no sequence homology with plasmid DNA of serotypes O:3 and O:9 and therefore may be associated with the lethal factor for mice.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
147
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
107-15
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6822745-Agglutinins,
pubmed-meshheading:6822745-Animals,
pubmed-meshheading:6822745-Base Sequence,
pubmed-meshheading:6822745-DNA, Bacterial,
pubmed-meshheading:6822745-Electrophoresis, Agar Gel,
pubmed-meshheading:6822745-Feces,
pubmed-meshheading:6822745-Food Microbiology,
pubmed-meshheading:6822745-Guinea Pigs,
pubmed-meshheading:6822745-Humans,
pubmed-meshheading:6822745-Mice,
pubmed-meshheading:6822745-Nucleic Acid Hybridization,
pubmed-meshheading:6822745-Plasmids,
pubmed-meshheading:6822745-Yersinia enterocolitica
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pubmed:year |
1983
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pubmed:articleTitle |
Plasmids of human strains of Yersinia enterocolitica: molecular relatedness and possible importance for pathogenesis.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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