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The effects of Listeria monocytogenes treatment on some functions of peritoneal macrophages in tumor-bearing rats were evaluated. In particular phagocytosis and intracellular killing of Escherichia coli and Candida albicans and chemotactic response to activated serum were studied in untreated and treated animals. Different restoration of macrophage functions, depressed in tumor-bearing rats, was obtained by treatment with whole formolinated L. monocytogenes or its crude extract.
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