Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1983-4-15
pubmed:abstractText
Rates of entry and oxidation of D(-)-3-hydroxybutyrate (DBHB) and glucose and their contribution to the total metabolic production of CO2 were studied in fed and 48-hr fasted Leghorn roosters using primed constant intravenous infusions of NaH14CO3, D(-)-3-[3-14C]-hydroxybutyrate, and D-[U-14C] glucose. Fasting increased plasma DBHB concentrations sixfold but did not change plasma glucose levels. In both states of nutrition, rates of CO2 production were identical (P greater than .05). Mean fractions of the total CO2 derived from DBHB and glucose in fed and fasted chickens, respectively, were: DBHB, 1.7 and 9.9% (P less than .001); glucose, 29 and 10% (P less than .001). Entry rates of DBHB and glucose in fed chickens were 276 and 5936 mumoles/hr per kg (P less than .001), respectively, and in starved birds were 1703 and 2204 mumoles/hr per kg (P less than .001), respectively. Fasting increased the oxidation rate of DBHB from 124 to 737 mumoles/hr per kg (P less than .001) and decreased the oxidation rate of glucose from 1491 to 525 mumoles/hr per kg (P less than .001). During fasting, glucose homeostasis is maintained in part by concomitant decreases in glucose entry and oxidation rates. The results are discussed with reference to the sparing effect of DBHB on glucose oxidation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0032-5791
pubmed:author
pubmed:issnType
Print
pubmed:volume
61
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2435-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Rates of entry and oxidation of D(-)-3-hydroxybutyrate and glucose in fed and fasted chickens.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't