Linked Life Data

6819502

Source:http://linkedlifedata.com/resource/pubmed/id/6819502

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1983-4-15
pubmed:abstractText
The ocular damage in mouse pups produced by purified Pseudomonas aeruginosa exotoxin A was examined microscopically following toxin A injection beneath the fused eyelid. In contrast to infection, in which lysis of ocular surface epithelium occurs within minutes, toxin A does not induce any lytic changes until 5 h after injection. Additionally, no phagocytic cellular response to toxin A was observed, whereas in infection, this response is seen within 1 h. We conclude that toxin A is not the bacterial extracellular factor responsible for mediating the rapid early destruction of the ocular epithelium allowing bacterial penetration and dissemination.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0030-3747
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
401-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Experimental Pseudomonas exotoxin A mediated ocular damage in mouse pups: microscopic observations.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.