Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1983-4-15
pubmed:abstractText
The effect of injection of an anesthetic dose of ketamine (70mg/kg) followed by xylazine (5mg/kg) on blood levels of luteinizing hormone and follicle stimulating hormone was measured in female rabbits. The drug combination caused a measurable suppression of follicle stimulating hormone levels in both castrated does and during the postovulatory follicle stimulating hormone surge in mated rabbits. Blood luteinizing hormone was low in these two animal model systems and was not further suppressed by ketamine-xylazine injections. When mated rabbits were injected with the drugs immediately postcoitum, ovulation and the preovulatory surge of luteinizing hormone and follicle stimulating hormone failed to occur in two of six treated animals. The results of these studies showed that ketamine-xylazine injections suppressed certain episodes of gonadotropin release in the female rabbit. However, the suppression was transitory and without apparent permanent effect.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0023-6764
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
619-21
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Effects of ketamine-xylazine anesthesia on blood levels of luteinizing hormone and follicle stimulating hormone in rabbits.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.