Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
Pt 3
pubmed:dateCreated
1983-2-14
pubmed:abstractText
Scalp hair samples were obtained from 11 children with mucopolysaccharidosis (MPS, types I, II and III) in order to study the micromorphological structure of the hair shafts. To evaluate the morphological variation longitudinal hair preparations and cross-sections were investigated by light microscopy and additionally scanning electron microscopy was employed to demonstrate the surface structure. It is shown that the mean hair shaft diameter in MPS-patients, separated into two age groups, is not significantly different from the mean value in normal children of the same age, whereas the wider range of diameters and, in connection with it, the increased medulla content seems to be a characteristic feature of MPS. The most striking deviations were observed in the cross-sections, particularly in MPS III/A patients: varying polygonal shapes and an abnormal pigment distribution. According to these cross-sections the hair surface exhibited severe deformities in the scanning electron microscope, i.e. distortions of hair, irregular nodes and longitudinal grooves. In MPS I and II similar abnormalities were found.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0022-264X
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
193-202
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Observations on hair shaft morphology in mucopolysaccharidoses.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't