Linked Life Data

6816273

Source:http://linkedlifedata.com/resource/pubmed/id/6816273

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
22
pubmed:dateCreated
1983-2-25
pubmed:abstractText
Phosphorus-31 nuclear magnetic resonance spectroscopy was used to study southern bean mosaic virus (SBMV) in its native and ethylenediaminetetraacetic acid treated forms at various pH values in the range 4.5-9.0. The degree of swelling in the latter form is a critical function of pH. Spin-lattice relaxation time (T1), line-width, and nuclear Overhauser effect (NOE) measurements were made at 40.51, 80.98, and 190.3 MHz. The results indicate that the RNA phosphate groups in native SBMV exhibit low-amplitude internal motions on a nanosecond time scale while the phosphate groups of swollen virus exhibit large-amplitude, more rapid, internal motions. A spread of T1 and NOE values is measured at intermediate stages in the swelling process. A simple explanation, consistent with the data, is that the RNA core of the virus undergoes a two-state phase transition from a relatively rigid, compact solid form in the native SBMV to a mobile, solvated state in the fully swollen particle.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0006-2960
pubmed:author
pubmed:issnType
Print
pubmed:day
26
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5390-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Phosphorus-31 nuclear magnetic resonance study of internal motion in ribonucleic acid of southern bean mosaic virus.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.