rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
1982-12-21
|
pubmed:abstractText |
Benzyl-2,5-diacetoxybenzoate (BDAB) was tested for anti-inflammatory activity on experimentally inflamed skin. Human abdominal skin was irradiated with three minimal erythema doses of UV-B (290-320nm) radiation to give a maximum erythema at 24 hours with an associated rise in PGE2 and PGF2 alpha levels measured by gas chromatography-mass spectrometry. Topical application of a 1% w/w preparation of BDAB neither decreased the evoked erythema nor diminished the rise in PGE2 and PGF2 alpha concentrations. BDAB, applied topically, was judged to be ineffectual as an anti-inflammatory agent in UV-B erythema.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0262-1746
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
35-43
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6813876-Aged,
pubmed-meshheading:6813876-Arachidonic Acid,
pubmed-meshheading:6813876-Arachidonic Acids,
pubmed-meshheading:6813876-Chromatography, High Pressure Liquid,
pubmed-meshheading:6813876-Dinoprostone,
pubmed-meshheading:6813876-Erythema,
pubmed-meshheading:6813876-Female,
pubmed-meshheading:6813876-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:6813876-Humans,
pubmed-meshheading:6813876-Hydroxybenzoic Acids,
pubmed-meshheading:6813876-Middle Aged,
pubmed-meshheading:6813876-Prostaglandins E,
pubmed-meshheading:6813876-Prostaglandins F,
pubmed-meshheading:6813876-Skin,
pubmed-meshheading:6813876-Ultraviolet Rays
|
pubmed:year |
1982
|
pubmed:articleTitle |
Levels of prostaglandins and arachidonic acid in UV-B irradiated human skin before and after topical application of benzyl-2,5-diacetoxybenzoate, a salicylic acid derivative.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|