Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1982-12-18
pubmed:abstractText
Experiments were conducted to determine the metabolic fate of threonine in chicks fed threonine-imbalanced diets. Threonine imbalance was produced by the addition of 3% serine to a threonine-limited diet, and prevented by the addition of 0.2% threonine to the diet. Serine decreased plasma and liver free threonine concentrations, and increased hepatic threonine dehydrogenase and threonine aldolase activities. All changes, including reduced food intake, appeared to occur within 1 day of feeding the imbalanced diet. Despite the decrease in free threonine concentrations and the increase in threonine aldolase and threonine dehydrogenase activities, net threonine catabolism was not markedly increased. This was evidenced by similar amounts of 14CO2 exhaled by chicks fed control and imbalanced diets containing L-[U-14C] threonine, and by similar growth of chicks that were forced-fed both diets to maintain equivalent food intake. It is possible that increases in threonine catabolism contribute to depressions of plasma and tissue threonine concentrations. However, the growth depression caused by serine-induced threonine imbalance is due to depressed food intake.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0022-3166
pubmed:author
pubmed:issnType
Print
pubmed:volume
112
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2177-86
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Threonine metabolism of chicks fed threonine-imbalanced diets.
pubmed:publicationType
Journal Article