Linked Life Data

6813349

Source:http://linkedlifedata.com/resource/pubmed/id/6813349

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3 Suppl
pubmed:dateCreated
1982-12-21
pubmed:abstractText
OKT10 is a monoclonal antibody which recognizes an antigenic structure of 45,000 daltons which is present on precursor T and B cells, activated T cells and some monocytes. In this study, this antibody was shown to react strongly with the surface membrane of plasma cells. In addition, OKT10 can be used to study final B cell maturation since the OKT10 antigen is expressed on mature lymphocytes and lymphoplasmacytic cells. Acquisition of OKT10 reactivity occurs in an inverse or opposite relationship to the presence of Ia-like antigenic expression. Therefore, these two antigens can be employed as complementary opposite reactants for the study of mature B cell malignancies, such as CLL, multiple myeloma, and Waldenström malignancy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0271-9142
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
67S-74S
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Two monoclonal antibodies (OKIa1 and OKT10) for the study of the final B cell maturation.
pubmed:publicationType
Journal Article