Linked Life Data

6809413

Source:http://linkedlifedata.com/resource/pubmed/id/6809413

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1982-10-21
pubmed:abstractText
Antisera were raised against the long and short form of mouse and human 7-S collagen and against type IV collagens solubilized by acid extraction or limited digestion with pepsin. All the antisera showed strong binding for 7-S collagen in radioimmunoassays demonstrating that the 7-S domain which serves as a cross-linking region of type IV collagen is the most immunogenic portion of the molecule. Cross-reaction studies and analysis of fragments showed a complex antigenic structure including some determinants common to the long and short form of 7-S collagen and others unique for the long form. Purified antibodies against 7-S collagen reacted in indirect immunofluorescence with almost all basement membranes of the body indicating that the 7-S domain is a common structural element of type IV collagens.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0174-173X
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
419-32
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Immunological characterization of the 7-S domain of type IV collagens.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't