Linked Life Data

6808727

Source:http://linkedlifedata.com/resource/pubmed/id/6808727

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-9-10
pubmed:abstractText
The effect of halofuginone (Stenorol) on schizonts of Theileria parva was studied by means of the electron microscope. After administration of 1,2 mg halofuginone per kg, it was observed that infected lymphocytes burst apart, whereas the intracellular parasites were at first little affected, showing some expansion of the perinuclear spaces. Once they were released from the cells, the schizonts degenerated completely. Apparently they are not capable of surviving outside the host cells. Probably this is due to the lack of a pellicle, which is characteristic for motile (i.e. normally extracellular) stages. The destruction of parasitized host cells occurred very rapidly, so that no infected cells could be observed 126 h after treatment. Uninfected lymphocytes were not affected by the drug.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0303-4208
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
231-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Electron microscopical study on the effect of halofuginone on Theileria parva.
pubmed:publicationType
Journal Article