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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1982-7-22
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pubmed:abstractText |
Immunoglobulin M (IgM) was isolated from serum of the chum salmon (Oncorhynchus keta) by means of ion-exchange chromatography followed by gel filtration. The purified chum salmon IgM had a mol. wt of 730,000 and a tetrameric structure. However, a fraction of tetrameric IgM was considered to be non-covalently associated molecules. The amino acid composition was determined for the chum salmon micro-and L-chains and was found to be similar to that reported for other teleost fish micro- and L-chains. No J-chain- like component could be identified in the salmon IgM by either alkaline urea polyacrylamide gel electrophoresis or by the immunological cross-reaction with antisera to the human and chicken J-chain. The immunoglobulin cross-reactivity between the chum salmon micro-chain and that of 22 other fishes was tested, and only micro-chains from the family Salmonidae revealed cross-reactivity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0161-5890
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
95-103
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:6804794-Amino Acids,
pubmed-meshheading:6804794-Animals,
pubmed-meshheading:6804794-Antibodies, Anti-Idiotypic,
pubmed-meshheading:6804794-Cross Reactions,
pubmed-meshheading:6804794-Immunoglobulin J-Chains,
pubmed-meshheading:6804794-Immunoglobulin Light Chains,
pubmed-meshheading:6804794-Immunoglobulin M,
pubmed-meshheading:6804794-Immunoglobulin mu-Chains,
pubmed-meshheading:6804794-Macromolecular Substances,
pubmed-meshheading:6804794-Molecular Weight,
pubmed-meshheading:6804794-Salmon,
pubmed-meshheading:6804794-Species Specificity
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pubmed:year |
1982
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pubmed:articleTitle |
Studies on subunit components of immunoglobulin M from a bony fish, the chum salmon (Oncorhynchus keta).
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pubmed:publicationType |
Journal Article
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