Linked Life Data

6795025

Source:http://linkedlifedata.com/resource/pubmed/id/6795025

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1982-1-9
pubmed:abstractText
The concentration of dopamine (DA) in pituitary stalk plasma of cycling female rats during diestrus was approximately 7 times that in stalk plasma of intact male rats, and the rate of DA synthesis in the median eminence of diestrous female rats was 5 times that in the median eminence of intact male rats. DA concentrations in pituitary stalk plasma of castrated adult male rats, orchiectomized as adults or as 1-day-old neonates, did not differ significantly from those of intact adult male rats. However, treatment of male rats with 17 beta-estradiol benzoate for 3 days resulted in a significant (P less than 0.005) increase in the concentration of DA in pituitary stalk plasma. DA concentrations in stalk plasma of adult female rats, ovariectomized as adults or treated with testosterone propionate (50 micrograms) on day 1 of life, did not differ appreciably from those of diestrous female rats. However, DA concentrations in stalk plasma of adult female rats that had been ovariectomized on day 14 of life were significantly (P less than 0.01) lower than those of diestrous female rats. In view of these results, it is concluded 1) that there is a sex-related difference in the release of DA from tuberoinfundibular neurons into hypophysial portal blood, and 2) that this difference is not due to a suppressive action of androgen on the secretion of DA in the male rat, but is a consequence of a stimulatory action of estrogen on the release of DA in the female rat.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0013-7227
pubmed:author
pubmed:issnType
Print
pubmed:volume
109
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1394-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Sex-related difference in the release of dopamine into hypophysial portal blood.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.