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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1981-12-21
|
| pubmed:abstractText |
Beta-Galactosidase was partially restored by protease inhibitors, leupeptin, chymostatin and E-64 in cultured fibroblasts from three patients with beta-galactosidase-neuraminidase deficiency. Pepstatin did not activate this enzyme. Neuraminidase was not affected by any of these compounds in the culture medium. It was concluded that the activating effect was produced by a specific inhibition of thiol proteases.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0021-924X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
90
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
271-3
|
| pubmed:dateRevised |
2007-12-19
|
| pubmed:meshHeading |
pubmed-meshheading:6793566-Cells, Cultured,
pubmed-meshheading:6793566-Enzyme Activation,
pubmed-meshheading:6793566-Fibroblasts,
pubmed-meshheading:6793566-Humans,
pubmed-meshheading:6793566-Lactose Intolerance,
pubmed-meshheading:6793566-Neuraminidase,
pubmed-meshheading:6793566-Protease Inhibitors,
pubmed-meshheading:6793566-Skin,
pubmed-meshheading:6793566-beta-Galactosidase
|
| pubmed:year |
1981
|
| pubmed:articleTitle |
Beta-galactosidase-neuraminidase deficiency: restoration of beta-galactosidase activity by protease inhibitors.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|