Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1981-12-21
pubmed:abstractText
The Bacillus subtilis 168 chromosome was found to share extensive homology with the genome of bacteriophage phi 3T. At least three different regions of the bacterial genome hydridized to ribonucleic acid complementary to phi 3T deoxyribonucleic acid (DNA). The thymidylate synthetase gene, thyA, of B. subtilis and the sequences adjacent to it were shown to be homologous to the region in the phi 3T DNA containing the phage-encoded thymidylate synthetase gene, thyP3. SP beta, a temperate bacteriophage known to be integrated into the B. subtilis 168 chromosome, was demonstrated to be closely related to phi 3T. Other regions of the bacterial genome were also found to hybridize to the phi 3T probe. The nature and location of these sequences in the bacterial and phage chromosomes were not identified. It was shown however, that they were not homologous to either the thyP3 gene or the DNA surrounding the thyP3 gene. The chromosomes of other Bacillus species were also screened for the presence of phi 3T homologous sequences, and the thyP3 gene was localized in the linear genomes of phages phi 3T and rho 11 by heteroduplex mapping. It is suggested that the presence of sequences of phage origin in the B. subtilis 168 chromosome might contribute to the restructuring and evolution of the viral and bacterial DNAs.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-1057486, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-1195397, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-14193626, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-16590310, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-169002, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-169042, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-169051, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-169095, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-193382, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-208776, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-242001, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-332064, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-401505, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-407445, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-412726, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-4216763, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-4594471, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-4633907, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-4894690, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-4919542, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-4977986, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-4979518, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-4999722, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-5231757, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-62060, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-6270056, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-787541, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-795415, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-824459, http://linkedlifedata.com/resource/pubmed/commentcorrection/6793558-825858
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0021-9193
pubmed:author
pubmed:issnType
Print
pubmed:volume
148
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
91-100
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Distribution of bacteriophage phi 3T homologous deoxyribonucleic acid sequences in Bacillus subtilis 168, related bacteriophages, and other Bacillus species.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.