Linked Life Data

6790476

Source:http://linkedlifedata.com/resource/pubmed/id/6790476

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
Pt 2
pubmed:dateCreated
1981-10-25
pubmed:abstractText
David and his collaborators have reported that adult Drosophila melanogaster survive longer on 2 per cent ethanol than on distilled water, but that the increased survival on ethanol does not occur in mutant flies lacking alcohol dehydrogenase activity. This has led us to enquire if the polymorphic alleles at the alcohol dehydrogenase locus (AdhF and AdhS), which code for enzymes with different activities, affect survival on low concentrations of ethanol. Flies were kept in sealed glass chambers containing either 2 per cent ethanol or distilled water. In four experiments, comprising a total of 126 replicates, the proportion of surviving FF flies, relative to SS, was greater on ethanol than on water. In two experiments the excess was highly significant. It appears that FF flies are better able than SS to use ethanol as food. Our results support the view that selection acts directly on the Adh polymorphism.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0018-067X
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
219-26
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Selection associated with the alcohol dehydrogenase locus in Drosophila melanogaster: differential survival of adults maintained on low concentrations of ethanol.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't