Linked Life Data

6790131

Source:http://linkedlifedata.com/resource/pubmed/id/6790131

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-10-29
pubmed:abstractText
Immunohistochemical staining showed that the adult isozyme of sn-glycerol-3-phosphate dehydrogenase (GPDH) was localized in two populations of cells in the mouse cerebellum. Staining was not detectable until after 10 days of age, thus correlating with the onset of accumulation of the adult enzyme. The two cell populations were identified as Bergmann glia and oligodendroglia on the basis of their morphology, distribution and their nearly complete absence from cerebella of mice with mutations (Weaver, wv/wv and Jimpy, jp/Y, respectively (which are known to reduce the numbers of these cell types. Biochemical analysis of these mutants suggests that Bergmann glia contribute approximately 60% of the total cerebellar GPDH activity while the contribution of oligodendroglia in the cerebellum is negligible. In addition, immunohistochemical staining of the rat cerebellum showed a distribution of this enzyme similar to that of the mouse. However, oligodendroglia of the rat stained more intensely than did the Bergmann glia.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:volume
227
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
341-54
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Immunohistochemical localization of sn-glycerol-3-phosphate dehydrogenase in Bergmann glia and oligodendroglia in the mouse cerebellum.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.