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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1981-9-22
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pubmed:abstractText |
To investigate the mechanism of hypophosphatemia during total parenteral nutrition (TPN), changes in phosphate (P) contents in the liver and muscle of rats supported by TPN for 2 days at 270 cal/g were studied in 39 Sprague Dawley rats (200 g body weight), divided into 5 groups as follows: G-I: starved for 24 hr (n = 7); G-II: TPN (5 mEq P/1000 cal) after 24 hr starvation (n = 7); G-III: starved for 4 days (n = 7); G-IV: TPN (5 mEq P/1000 cal) after 4 days starvation (n = 9); G-V: TPN (35 mEq P/1000 cal) after 4 days starvation (n = 9). P contents of the tissues were measured colorimetrically. Results indicated that muscle P content decreased in the depleted rat supported by TPN with low P intake, while an increase in P content in the liver was a constant finding in each TPN group. Increase in P intake tended to preserve the P content in the muscle. These findings suggest that the changes in P distribution in major body tissues must be considered in addition to the changes in the serum inorganic P levels to evaluate an adequate P requirement for TPN.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0148-6071
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
189-92
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pubmed:dateRevised |
2007-2-21
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pubmed:meshHeading |
pubmed-meshheading:6788967-Animals,
pubmed-meshheading:6788967-Body Weight,
pubmed-meshheading:6788967-Liver,
pubmed-meshheading:6788967-Muscles,
pubmed-meshheading:6788967-Nutritional Requirements,
pubmed-meshheading:6788967-Parenteral Nutrition,
pubmed-meshheading:6788967-Parenteral Nutrition, Total,
pubmed-meshheading:6788967-Phosphates,
pubmed-meshheading:6788967-Phosphorus,
pubmed-meshheading:6788967-Rats,
pubmed-meshheading:6788967-Starvation,
pubmed-meshheading:6788967-Time Factors
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pubmed:articleTitle |
Changes in phosphorus distribution during total parenteral nutrition.
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pubmed:publicationType |
Journal Article
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