rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
1981-7-9
|
pubmed:abstractText |
Rabbit eyes were inoculated with different concentrations of Pseudomonas aeruginosa. Copious irrigation and topical Neosporin solution decreased surface contamination by 90% as compared to controls. Ps. aeruginosa added to M-K medium and stored at 4 degree C remained viable for 6 days and multiplied rapidly when the medium was incubated at 35 degree C. Adding penicillin and streptomycin (125 units/ml each) suppressed, but did not prevent this growth. Gentamicin (100 micrograms/ml) suppressed growth in all vials by 72 hours at 4 degree C. These studies show that gentamicin is clearly superior to penicillin and streptomycin in preventing Ps. aeruginosa contamination of donor corneas. It is suggested that donor eyes and M-K media be routinely cultured upon arrival at the eye-bank and the time of surgery in order to avoid or immediately treat gentamicin-resistant donor cornea contamination.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0003-4886
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
429-32
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:6786161-Animals,
pubmed-meshheading:6786161-Anti-Bacterial Agents,
pubmed-meshheading:6786161-Bacitracin,
pubmed-meshheading:6786161-Culture Media,
pubmed-meshheading:6786161-Drug Combinations,
pubmed-meshheading:6786161-Eye,
pubmed-meshheading:6786161-Gentamicins,
pubmed-meshheading:6786161-Neomycin,
pubmed-meshheading:6786161-Organ Preservation,
pubmed-meshheading:6786161-Penicillins,
pubmed-meshheading:6786161-Polymyxin B,
pubmed-meshheading:6786161-Pseudomonas aeruginosa,
pubmed-meshheading:6786161-Rabbits,
pubmed-meshheading:6786161-Streptomycin
|
pubmed:year |
1980
|
pubmed:articleTitle |
Resistance of Pseudomonas aeruginosa to modern eye-banking technique.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|