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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1981-6-25
|
| pubmed:abstractText |
Methylprednisolone, 30 mg/kg body weight, was given to dogs 30 min and 4 h after injection of monocrotaline to produce noncardiogenic pulmonary edema. Control animals received monocrotaline but not corticosteroids. After 6 h the steroid-treated animals demonstrated significantly butter gas exchange and significantly less pulmonary edema. A possible mechanism of this beneficial effect of steroids is inhibition of complement-leukocyte interactions which may mediate pulmonary microvascular injury. The results lend some support to the clinical practice of short-term pharmacologic doses of steroids in noncardiogenic pulmonary edema.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0342-4642
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
7
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
121-4
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:6783692-Animals,
pubmed-meshheading:6783692-Disease Models, Animal,
pubmed-meshheading:6783692-Dogs,
pubmed-meshheading:6783692-Hemodynamics,
pubmed-meshheading:6783692-Methylprednisolone,
pubmed-meshheading:6783692-Monocrotaline,
pubmed-meshheading:6783692-Plants, Toxic,
pubmed-meshheading:6783692-Pulmonary Circulation,
pubmed-meshheading:6783692-Pulmonary Edema,
pubmed-meshheading:6783692-Pyrrolizidine Alkaloids,
pubmed-meshheading:6783692-Senecio
|
| pubmed:year |
1981
|
| pubmed:articleTitle |
Effect of methylprednisolone on experimental noncardiogenic pulmonary edema.
|
| pubmed:publicationType |
Journal Article
|