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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5-6
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pubmed:dateCreated |
1981-5-13
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pubmed:abstractText |
Bacteriological filtrates of three strains of Pseudomonas aeruginosa were compared with respect to inhibitory effect on ciliary movements and a quantitative difference was established between them. The cilia inhibitory effect was strictly concentration-dependent and was resistant to heating. The ciliotoxic effect disappeared from filtrates after chloroform extraction. The chloroform-extracted sediment ws dissolved in physiological saline and the solution revealed an inhibitory effect on cilia. Involvement of endotoxin is not probable, since E. coli endotoxin in a high concentration was not toxic. Partially purified Pseudomonas aeruginosa phenazine pigment as well as haemolysin inhibited ciliary activity and the effect was standardized in the present experimental system.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0001-6489
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
90
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
462-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6782825-Animals,
pubmed-meshheading:6782825-Bacteriological Techniques,
pubmed-meshheading:6782825-Cilia,
pubmed-meshheading:6782825-Hemolysin Proteins,
pubmed-meshheading:6782825-Mucus,
pubmed-meshheading:6782825-Pseudomonas aeruginosa,
pubmed-meshheading:6782825-Pyocyanine,
pubmed-meshheading:6782825-Rabbits,
pubmed-meshheading:6782825-Trachea
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pubmed:articleTitle |
The mucociliary activity of the respiratory tract. I. Inhibitory effects of products of Pseudomonas aeruginosa on rabbit trachea in vitro.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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