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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1981-4-21
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pubmed:abstractText |
Normal adult Chacma baboons were investigated with reference to their basic immunological parameters, including serum immunoglobulin concentrations, proportions of T- and B-lymphocytes in the peripheral blood, and lymphocyte response to activators. As rabbit antihuman antisera to immunoglobulins were used for the serum immunoglobulin determinations, cross-reactivity between human and baboon immunoglobulins was evaluated, and it was found that human and baboon IgG and IgM were both completely cross-reactive, while IgA was partially cross-reactive. The serum immunoglobulin concentrations, proportions of T- and B-lymphocytes, and response to activators were found to be similar to those of man. These findings indicate that the Chacma baboon would be a useful and relevant model for the study of cellular and humoral immunology.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0023-6764
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1018-21
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6780725-Animals,
pubmed-meshheading:6780725-B-Lymphocytes,
pubmed-meshheading:6780725-Cross Reactions,
pubmed-meshheading:6780725-Female,
pubmed-meshheading:6780725-Humans,
pubmed-meshheading:6780725-Immunodiffusion,
pubmed-meshheading:6780725-Immunoglobulins,
pubmed-meshheading:6780725-Lymphocyte Activation,
pubmed-meshheading:6780725-Male,
pubmed-meshheading:6780725-Papio,
pubmed-meshheading:6780725-Rosette Formation,
pubmed-meshheading:6780725-T-Lymphocytes
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pubmed:year |
1980
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pubmed:articleTitle |
Normal cellular and humoral immunologic parameters in the baboon (Papio ursinus) compared to human standards.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|