Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1981-4-24
pubmed:abstractText
Circulating antibodies were detected before treatment in the serum of 18 of 40 patients with newly acquired tuberculosis and of eight of 12 patients with reactivated tuberculosis by microimmunodiffusion tests with unheated mycobacterial culture filtrate, arabinogalactan, arabinomannan, and a specific culture filtrate fraction. Some patients responded to a single antigen, while others responded to two and at times four or more. Some of these antibodies reacted with polysaccharides, but many reacted with protein. Antibiotic treatment increased the percentage of responders from 46% to 60% in new cases and from 66% to 75% in relapse cases and increased the concentration of antibodies. In evaluation of serologic tests in tuberculosis, the effect of prior chemotherapy must be weighed. These microimmunodiffusion tests appear to be specific for Mycobacterium tuberculosis.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0022-1899
pubmed:author
pubmed:issnType
Print
pubmed:volume
142
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
825-34
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Antibodies to mycobacteria in human tuberculosis. I. Development of antibodies before and after antimicrobial therapy.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Controlled Clinical Trial, Research Support, Non-U.S. Gov't