Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1981-2-24
pubmed:abstractText
We utilized the circumoval precipitin (COP) test, Ouchterlony immunodiffusion, and the enzyme-linked immunosorbent assay (ELISA) for the serodiagnosis of human infection with Schistosoma mansoni or S. haematobium, or with both species of schistosome. Only the COP test correctly identified all of those with schistosome infection, although differentiation as to schistosome species was impossible. Circumoval precipitates around S. haematobium eggs from human urine were more numerous and larger than those around S. mansoni eggs obtained from mouse livers. Ouchterlony immunodiffusion with S. mansoni or S. haematobium worm extract failed to diagnose correctly approximately one of every five infected individuals. Mean absorption values of the S. mansoni soluble egg antigen (SEA) used in the ELISA were similar in serum samples from persons infected with either or both species of blood flukes. This suggests that S. mansoni SEA is not species-specific. The ELISA correctly identified, however, 30 of 32 infected individuals, indicating high sensitivity.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0002-9637
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1254-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Immunodiagnosis of infection with Schistosoma haematobium and S. mansoni in man.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't